Welcome to the Surveillance Knowledge Repository

Click on a topic under the Key Topic Areas section in the left column, then select a resource  from the list of resources that appear for that topic. You may also search for specific topics by entering one or more keywords in the Search bar. You can filter the search results by Content Type, Year, or Author Name.



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Detection of biological threat agents (BTAs) is critical to the rapid initiation of treatment, infection control measures, and public health emergency response plans. Due to the rarity of BTAs, standard methodology for developing syndrome definitions and measuring their validity is lacking.... Read more

Content type: Abstract

In this project we present a robust methodology for evaluating the fitness of the Semi-Naive Bayesian Network disease model structure used by Geographic Utilization of Artificial Intelligence in Real-Time for Disease Identification and Alert Notification (GUARDIAN) - a real-time, scalable,... Read more

Content type: Abstract

In 2016, the World Health Organization declared Zika virus a global public health emergency. Zika infection during pregnancy can cause microcephaly and other fetal brain defects. To facilitate clinicians’ ability to detect Zika, various syndrome definitions have been developed. 

Objective... Read more

Content type: Abstract

The Centers for Disease Control and Prevention case definition of influenza-like illness (ILI) as fever with cough and/or sore throat casts a wide net resulting in lower sensitivity which can have major implications on public health surveillance and response.



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Content type: Abstract

The primary goal of syndromic surveillance is early recognition of disease trends, in order to identify and control infectious disease outbreaks, such as influenza. For surveillance of influenza-like illness (ILI), public health departments receive data from multiple sources with varying degrees... Read more

Content type: Abstract

Adoption of electronic medical records is on the rise, due to the Health Information Technology for Economic and Clinical Health Act and meaningful use incentives. Simultaneously, numerous HIE initiatives provide data sharing flexibility to streamline clinical care. Due to the consolidated data... Read more

Content type: Abstract

Clinical quality measures (CQMs) are tools that help measure and track the quality of health care services. Measuring and reporting CQMs helps to ensure that our health care system is delivering effective, safe, efficient, patient-centered, equitable, and timely care. The CQM for influenza... Read more

Content type: Abstract

Processing free-text clinical information in an electronic medical record (EMR) may enhance surveillance systems for early identification of ILI outbreaks. However, processing clinical text using NLP poses a challenge in preserving the semantics of the original information recorded. In this... Read more

Content type: Abstract

In recent years, the threat of pandemic influenza has drawn extensive attention to the development and implementation of syndromic surveillance systems for early detection of ILI. Emergency department (ED) data are key components for syndromic surveillance systems. However, the lack of... Read more

Content type: Abstract

Effective real-time surveillance of infectious diseases must strike a balance between reliability and timeliness for early detection. Traditional syndromic surveillance utilizes limited sections of the EMR, such as chief complaints and/or diagnosis. However, other sections of the EMR may contain... Read more

Content type: Abstract


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This Knowledge Repository is made possible through the activities of the Centers for Disease Control and Prevention Cooperative Agreement/Grant #1 NU500E000098-01, National Surveillance Program Community of Practice (NSSP-CoP): Strengthening Health Surveillance Capabilities Nationwide, which is in the interest of public health.

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